Conditions
11 evidence-based articles
Conditions covers the symptom you actually have, rather than the product aisle you happen to be standing in. There are four guides here: IBS, acid reflux and GERD, constipation, and bloating. Each one starts from the condition, walks through the treatments that have been trialled for it, and ranks them by how strong the evidence is — not by what is easiest to sell.
That produces some answers people do not expect. Gut-directed hypnotherapy edges out peppermint oil and probiotics in the IBS trial data. MiraLAX (PEG 3350) beats fiber and short-term stimulant laxatives for chronic constipation. For reflux, a fast H2 blocker like Pepcid and a daily PPI like Prilosec or Nexium solve different problems, and which one is right depends on how often your symptoms occur. For bloating, enteric-coated peppermint oil has the best condition-specific evidence, ahead of the gas-focused products most people reach for first.
Each guide opens with a short direct answer, then explains the reasoning and the limits behind it, including when a symptom warrants seeing a doctor instead of buying anything. Read the guide for your symptom first; it will point you to the product ranking in Reviews if a supplement is genuinely part of the answer. Nothing here is medical advice or a diagnosis.
IBS-C vs IBS-D: How Symptoms and Treatment Differ
IBS-C vs IBS-D: how to tell which subtype you have, why it can switch, which tests doctors order, and which treatments the trial data support.
Constipation Relief: An Evidence-Based Guide (2026)
MiraLAX (PEG 3350) leads our 2026 evidence-based constipation relief ranking, ahead of fiber and short-term stimulant laxative options.
Is Leaky Gut Real? What's Proven and What Actually Helps
Is leaky gut real? Gut permeability is measurable in celiac, Crohn's and some IBS, but leaky gut syndrome isn't a diagnosis. Tests, glutamine, what helps.
Foods to Avoid With Acid Reflux: What the Evidence Says
Foods to avoid with acid reflux, ranked by evidence: coffee, chocolate, fatty meals, alcohol and spicy food, plus meal timing and a trigger diary.
Foods That Cause Bloating (and What to Eat Instead)
Foods that cause bloating, from beans and dairy to wheat and sugar-free sweets: why they bloat, gentler swaps, and how to find your own triggers.
The Gut Microbiome: An Evidence-Based Guide (2026)
What the gut microbiome is, what actually shapes it, and what probiotics, prebiotics, and microbiome tests can — and can't — do, based on the clinical evidence.
How to Fix Bloating: What Actually Works in 2026
Evidence-based bloating relief ranked for 2026: sustained-release peppermint oil (IBgard) leads, plus Iberogast, Beano, Gas-X, and ginger compared.
SIBO Diagnosis and Treatment: Symptoms, Breath Tests, Relapse
An evidence-based guide to SIBO diagnosis and treatment: symptoms, IBS overlap, breath test cut-offs and accuracy, rifaximin, relapse rates, and diet.
IBS Treatments That Actually Work: 2026 Evidence-Based Guide
IBS treatments ranked by evidence: gut-directed hypnotherapy and peppermint oil lead the trial data, with probiotics a modest add-on.
Low-FODMAP Diet for IBS: An Evidence-Based Guide (2026)
How the low-FODMAP diet works for IBS, what the trials show, how to do all three phases, and when a simpler diet may work as well.
Acid Reflux & GERD: A Complete Treatment Guide (2026)
2026 guide to acid reflux and GERD — antacids, H2 blockers like Pepcid, and PPIs like Prilosec and Nexium, compared by use case.